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Is it just as good as Ozempic? Ozempic and Rybelsus are made by the same manufacturer, Novo Nordisk, and have the same active ingredient, semaglutide. Semaglutide is a GLP-1 receptor agonist, one of a family of drugs that mimic the effect of a hormone that stimulates insulin secretion and prompts feelings of hunger. Semaglutide was originally developed and approved to treat type 2 diabetes, but it turned out to be one of the greatest weight loss drugs ever invented. To assess the potency of each drug, we can compare their results in studies that tested similar populations.

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