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Sertraline is a selective serotonin reuptake inhibitor SSRI indicated to treat major depressive disorder, social anxiety disorder and many other psychiatric conditions. Sertraline is a popular antidepressant medication commonly known as a selective serotonin reuptake inhibitor SSRI, and is similar to drugs such as Citalopram and Fluoxetine. Despite marked structural differences between compounds in this drug class, SSRIs exert similar pharmacological effects. Several weeks of therapy with sertraline may be required before beneficial effects are noticed. Sertraline displays enhanced safety or tolerability than other classes of antidepressants, which frequently cause high levels of drowsiness, dizziness, blurred vision, and other undesirable effects. Sertraline selectively inhibits the reuptake of serotonin 5-HT at the presynaptic neuronal membrane, thereby increasing serotonergic activity. This results in an increased synaptic concentration of serotonin in the CNS, which leads to numerous functional changes associated with enhanced serotonergic neurotransmission. It has been hypothesized that obsessive-compulsive disorder, like depression, is also caused by the disregulation of serotonin. In animal studies, chronic administration of sertraline results in down-regulation of brain norepinephrine receptors.
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It works by increasing the levels of serotonin, a chemical messenger in the brain. Serlift Eris Lifesciences Ltd.
- Sertraline is used to treat depression, obsessive-compulsive disorder, panic attacks, posttraumatic stress disorder and social anxiety disorder.
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Sertraline, like citalopram Celexa, escitalopram Lexapro, fluoxetine Prozac, fluvoxamine Luvox, and paroxetine Paxil, Pexeva, belongs to a class of medications known as selective serotonin reuptake inhibitors SSRIs - similar to venlafaxine Effexor and different from NDRI medications like Wellbutrin. Sertraline works by inhibiting the reuptake of serotonin 5-HT - a chemical neurotransmitter - by neurons in the central nervous system.
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