He has good proficiency in Technology transfer, Spectroscopy, Stereochemistry, Synthesis, Polymorphism etc. It is also used off-label as an adjunct in treating clinical depression. Like many other anticonvulsant medications, lamotrigine also seems to act as an effective mood stabilizer, and has been the first US Food and Drug Administration FDA -approved drug for this purpose since lithium, a drug approved almost 30 years earlier. It is approved for the maintenance treatment of bipolar type I. Lamotrigine is generally accepted to be a member of the sodium channel blocking class of antiepileptic drugs, but it could have additional actions since it has a broader spectrum of action than other sodium channel antiepileptic drugs such as phenytoin and carbamazepine and is effective in the treatment of the depressed phase of bipolar disorder, where as other sodium channel blocking antiepileptic drugs are not.

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My doctor would not give me more than mg a day,and he told me that my last dose should be PM because Lamictal he said is like coffee,and if we take it late,we can not sleep. This is interesting as on my medication box it says to take at night and that it can cause drowsiness and dizziness. I can only tell you what I've been told by my doc. At its lowest level, Lamictal is an anti-anxiety drug. I'm at MG, possibly changing to MG. Just because I've been having a lot of accidents falling down the stairs, etc.

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Dosage and administration. If therapy with Lamotrigine is considered necessary during pregnancy, the lowest possible therapeutic dose is recommended. Adverse skin reactions may occur, usually within the first 8 weeks after initiation of lamotrigine treatment. The side effects of Lamotrigine are rash, hypersensitivity syndrome possibly including rash, fever, facial edema, lymphadenopathy, hepatic dysfunction, blood disorders, disseminated intravascularcoagulation and multi-organ dysfunction, nausea, vomiting, diarrhoea, hepatic dysfunction; headache, fatigue, dizziness, sleep disturbances, tremor, movement disorders, agitation, confusion, hallucinations, occasional increase in seizure frequency, blood disorders including leucopenia, thrombocytopenia, pancytopenia, arthralgia, lupus erythematosus-like effect, photosensitivity, nystagmus, diplopia, blurred vision, conjunctivitis and suicidal ideation. Lamotrigine is contraindicated in patients with known hypersensitivity to the active substance or to any of the excipients.

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Lamotrigine, sold under the brand name Lamictal among others, is a medication used to treat epilepsy and stabilize mood in bipolar disorder. Common side effects include nausea, sleepiness, headache, vomiting, trouble with coordination, and rash. Lamotrigine was first marketed in Ireland in, 11 and approved for use in the United Lamitrin lamictal 300 mg in Lamotrigine is considered a first-line drug for primary generalized tonic-clonic seizures includes simple partial, complex partial, and secondarily generalized seizures such as focal-onset tonic-clonic seizures. It is also used as an alternative or adjuvant medication for partial seizures, such as absence seizure, myoclonic seizure, and atonic seizures.

Lamotrigine can cause serious rashes requiring hospitalization and discontinuation of treatment. The incidence of these rashes, which have included Stevens-Johnson syndrome, is approximately 0. However, the relatively limited treatment experience with lamotrigine ER makes it difficult to characterize the price of singulair generic and risk of serious rashes caused by treatment with lamotrigine ER. Other than age, there are as yet no factors identified that are known to predict the risk of occurrence or the severity of rash caused by lamotrigine. There are suggestions, yet to be proven, that the risk of rash may also be increased by coadministration of lamotrigine with valproate includes valproic acid and divalproex sodium, exceeding the recommended initial dose of lamotrigine, or exceeding the recommended dose escalation for lamotrigine.

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Lamictal is used alone or in combination with other drugs to treat seizures in adults and children with epilepsy. In addition, Lamictal is commonly prescribed to adults with bipolar disorder manic depression to delay episodes of depression and mania. Mania is defined as frenzied or abnormally excited moods. Lamictal is also prescribed off-label to treat clinical depression and migraine headaches. The FDA first approved Lamictal in as an anti-seizure medication. Approval to use the drug in the treatment of bipolar disorder was given in

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Youssef, Zubin Bhagwagar, Lamotrigine-associated rash: to rechallenge or not to rechallenge? The major burden of illness in bipolar disorder BD is in the depressive pole. These papers describe 44 cases of lamotrigine rechallenge. There are some characteristics of the rash that can help identify serious cases from benign ones. In addition, very slow titration of lamotrigine is crucial to the reduction of rash recurrence rate.

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