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We are leading exporter and manufacturer of Nimodipine Injection. Uses Nimodipine is used in the treatment of subarachnoid haemorrhage. How it works Nimodipine is a calcium channel blocker. It blocks the action of calcium on the blood vessel of the brain. This prevents changes in brain function after bleeding around the brain subarachnoid hemorrhage.

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Calcium antagonists reduce the proportion of patients with poor outcome and ischemic neurological deficits after aneurysmal subarachnoid hemorrhage aSAH. The evidence for nimodipine is not beyond every doubt, but given the potential benefits and modest risks associated with this treatment, against the background of a devastating natural history, oral nimodipine 60 mg every 4 h seems indicated in patients with aSAH. Counteractive measures, including the use of intravenous vasopressors, application of fluid bolus, or a reduction in oral nimodipine dosage 30 mg every 2 h, may be necessary to overcome profound repetitive hypotensive episodes. Significant drops in systolic ABP occurred in one third of patients after the start of IV nimodipine 81 of and after every tenth oral nimodipine intake 53 of during a study period of 15 days. The authors concluded that continuous invasive ABP monitoring should be considered in patients with aSAH on calcium antagonists.

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Nimodipine is isopropyl 2 - methoxyethyl 1, 4 - dihydro - 2, 6 - dimethyl - 4 - m-nitrophenyl - 3, 5 - pyridinedicarboxylate. Specific treatments for calcium channel blocker overdose should also be given promptly. The oral dose is 60 mg two 30 mg capsules every 4 hours for 21 consecutive days, preferably not less than one hour before or two hours after meals. If the capsule cannot be swallowed, e. The efficacy and safety of this method of administration has not been demonstrated in clinical trials. Patients with hepatic cirrhosis have substantially reduced clearance and approximately doubled Cmax.

Accidental injection of nimodipine can cause serious rarely fatal side effects such as low blood pressure, slow heartbeat. However, when the bleeding is in the brain, stopping blood flow causes more brain damage. Nimodipine is thought to work by relaxing narrowed blood vessels in the brain near the area of bleeding so buy nimotop iv can flow more easily. OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug but that may be prescribed by your health care professional. Use this drug for a condition that is listed in this section only if it has been so prescribed by your health care professional.

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Subarachnoid hemorrhage: Oral: 60 mg every 4 hours for 21 consecutive days. Note: Start therapy within 96 hours of the onset of subarachnoid hemorrhage. No dosage adjustment provided in manufacturer's labeling. However, nimodipine undergoes minimal renal elimination and dose adjustment may not be necessary. Not removed by hemo- or peritoneal dialysis; supplemental dose is not necessary. Note: Optimal management is not clearly defined Ref.

Despite all existing treatment approaches, aSAH, and the ensuing CV and DCI are the leading causes of morbidity and mortality in affected patients 1, 2. Intra-arterial digital subtraction angiography DSA is commonly used as a screening device for the identification of CV and focal cerebral ischemia CI 5. Furthermore, DSA allows for therapeutic endovascular interventions, such as balloon angioplasty and stenting in each intracranial artery if required 5. Still, the detailed delineation of the vessels may not be obtained when multiple stenoses are present, and DSA also constitutes an invasive method. In addition, CTP can be used in daily practice, or it can be used as a separate diagnostic tool without the need for magnetic resonance imaging MRI data to predict the outcomes of patients with aSAH 7, 8. Even though a conventional MRI provides anatomical details, it does not provide functional details on the dynamic process of ischemia and its elongation.

We always guarantee you the lowest price! Yes, we are open, actively processing buys nimotop iv and have taken steps to ensure that we remain open during these challenging times. Conditions Treated by Nimotop Brain aneurysms are more common than you might think and for the most part cause no symptoms or health issues.

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