Do not take lisinopril if you are pregnant. Lisinopril may harm the fetus. Lisinopril is used alone or in combination with other medications to treat high blood pressure in adults and children 6 years of age and older. It is used in combination with other medications to treat heart failure.

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Lisinopril is an oral medication that belongs to a class of medications known as an angiotensin-converting enzyme ACE inhibitors - similar to benazepril, captopril, enalapril and quinapril. ACE inhibitors like lisinopril Zestril are thought to lower blood pressure by suppressing the renin-angiotensin-aldosterone system. The effect on blood pressure is additive when lisinopril is utilized at the same time as a thiazide-type diuretic such as in a lisinopril - hydrochlorothiazide HCTZ combination.

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