The inactive ingredients in VOLTAREN include: hydroxypropyl methylcellulose, iron oxide, lactose, magnesium stearate, methacrylic acid copolymer, microcrystalline cellulose, polyethylene glycol, povidone, propylene glycol, sodium hydroxide, sodium starch glycolate, talc, titanium dioxide. Because clinical trials are conducted under widely varying conditions, adverse reaction rates observed in the clinical trials of a drug cannot be directly compared to rates in the clinical trials of another drug and may not reflect the rates observed in practice. Abnormal renal function, anemia, dizziness, edema, elevated liver enzymes, headaches, increased bleeding time, pruritus, rashes and tinnitus. Body as a Whole: fever, infection, sepsis. Cardiovascular System: congestive heart failure, hypertension, tachycardia, syncope. Hemic and Lymphatic System: ecchymosis, eosinophilia, leukopenia, melena, purpura, rectal bleeding, stomatitis, thrombocytopenia.

Without therapy, a gout flare usually resolves completely within a few days to several weeks, particularly in early disease. However, symptoms improve faster with treatment 1. Flares recur in the great majority of patients. With more frequent episodes, flares may be more severe and prolonged, and asymptomatic periods become shorter. The approach to asymptomatic hyperuricemia; the pathophysiology, clinical manifestations, and diagnosis of gout; and the prevention of recurrent gout after resolution of the gout flares are discussed separately However, these conditions would not preclude treatment with a nonsteroidal antiinflammatory drug NSAID or colchicine. The differential diagnosis and evaluation of gout is discussed separately.

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People who take nonsteroidal anti-inflammatory drugs NSAIDs other than aspirin such as diclofenac may have a higher risk of having a heart attack or a stroke than people who do not take these medications. These events may happen without warning and may cause death. Do not take an NSAID such as diclofenac if you have recently had a heart attack, unless directed to do so by your doctor. Tell your doctor if you or anyone in your family has or has ever had heart disease, a heart attack, or a stroke, if you smoke, and if you have or have ever had high cholesterol, high blood pressure, or diabetes. If you will be undergoing a coronary artery bypass graft CABG; a type of heart surgery, you should not take diclofenac right before or right after the surgery.

UK, remember your settings and improve government services. This analysis found that of patients allocated to diclofenac for a year, three more had major vascular events, compared with placebo. Patients with these conditions should be switched to an alternative treatment at their next routine appointment. Diclofenac treatment should only be initiated after careful consideration for patients with significant risk factors for cardiovascular events eg, hypertension, hyperlipidaemia, diabetes mellitus, smoking. Naproxen and low-dose ibuprofen are considered to have the most favourable thrombotic cardiovascular safety profiles of all non-selective NSAID. The lowest effective dose should be used for the shortest duration necessary to control symptoms.

Diclofenac penetrates deep into the skin and provides pain relief for up to 12 hours. Unlike cooling gels and heat patches that work only by physical action cooling or heating the skin, diclofenac works by relieving pain and reducing inflammation at the source. Compared with Voltaren Emulgel, Voltaren 12H Gel has double the concentration of the active ingredient diclofenac diethylamine. Voltaren 12H Gel does not have a strong odour, and usually an amount ranging in size from a cherry to a walnut will be enough, but it will depend on the size of the affected area. Use up to 14 days for soft tissue injuries, like sprains or strains, and 21 days for arthritis. Only use for longer periods on the advice of a doctor.

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