Caution: Monitor for signs and symptoms of post injection syndrome for at least 3 hours after administering olanzapine depot injection. The Pharmaceutical Benefits Advisory Committee recommended olanzapine depot injection for listing consistent with the listings of other long-acting antipsychotic injections for the treatment of schizophrenia. It is approved for maintenance treatment of schizophrenia in adults sufficiently stabilised during acute treatment with oral olanzapine. The PBS listing of olanzapine depot injection provides an additional long-acting atypical antipsychotic option to risperidone IM long-acting injection, the only other depot atypical antipsychotic approved and PBS listed for maintenance treatment in schizophrenia. Other antipsychotic depot options include the typical antipsychotics depot flupenthixol, fluphenazine, haloperidol and zuclopenthixol. Without a head-to-head, controlled comparison trial it is unclear how much depot olanzapine's effectiveness, safety, tolerability and patient acceptability differs from that of depot risperidone and other depot antipsychotics. Medication non-adherence is common and associated with poorer outcomes in people with schizophrenia.

Olanzapine is used orally for the symptomatic management of psychotic disorders e. In addition, oral olanzapine is used alone in adults and adolescents years of age or in conjunction with lithium or valproate in adults for the management of acute manic or mixed episodes associated with bipolar I disorder; the drug also is used for longer-term maintenance monotherapy in patients with this disorder. Short-acting olanzapine injection is used IM for the management of acute agitation in patients with bipolar disorder or schizophrenia. Long-acting olanzapine pamoate injection is used IM for the management of schizophrenia in adults. Olanzapine is used orally in combination with fluoxetine for the treatment of acute depressive episodes associated with bipolar I disorder in adults and pediatric patients years of age. The drug also is used orally in combination with fluoxetine for the acute and maintenance therapy of treatment-resistant depression.

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Common side effects include weight gain, movement disorders, dizziness, feeling tired, constipation, and dry mouth. Olanzapine was patented in and approved for medical use in the United States in The first-line psychiatric treatment for schizophrenia is antipsychotic medication; with olanzapine being one such medication. National Institute for Health and Care Excellence, the British Association for Psychopharmacology, and the World Federation of Societies for Biological Psychiatry suggest that there is little difference in effectiveness between antipsychotics in prevention of relapse, and recommend that the specific choice of antipsychotic be chosen based on a person's preference and the drug's side effect profile. Agency for Healthcare Research and Quality concludes that olanzapine is not different from haloperidol in the treatment of positive symptoms and general psychopathology, or in overall assessment, but that it is superior for the treatment of negative and depressive symptoms. In a comparison of 15 antipsychotic drugs in schizophrenia, olanzapine was ranked third in efficacy.

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Prozac 10mg vs 20mg Paroxetine is one of the selective serotonin reuptake inhibitors SSRIs used in the treatment of premature ejaculation PE. However, this use is not approved in many countries. We searched relevant randomized, controlled trials through May, using PubMed, Embase and. Adults—At first, 20 milligrams mg of fluoxetine and 5 mg of olanzapine once a day, taken in the evening. Your doctor may adjust your dose as needed. However, the dose is usually not more than 50 mg of fluoxetine and 12 mg of olanzapine per day.

Note that a combination medication containing olanzapine and fluoxetine is available. Your doctor can tell you more about this. Olanzapine is a generic drug. A generic drug is an exact copy of the active drug in a brand-name medication. Zyprexa is the brand-name medication that olanzapine is based on.

Zyprexa is used to treat the symptoms of psychotic conditions such as schizophrenia and bipolar disorder manic depression. The company sold more than 90 million rotisserie chickens last year. How much does Zyprexa cost? Zyprexa is a medication known as an atypical antipsychotic that is used to treat symptoms of schizophrenia. The drug is also sometimes prescribed to treat symptoms of bipolar disorder and treatment-resistant depression.

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