Imipramine is a drug used to treat depression. In multiple sclerosis, a low dose is sometimes used to treat pain, particularly nerve pain or altered sensations, such as burning feelings, pins and needles or stabbing pains. It can also be used for some mild bladder symptoms such as urinary frequency and incontinence. These change the balance of chemicals in the brain that pass messages between nerves. This alters the way in which the central nervous system reacts to pain. Imipramine also affects the rate at which urine is produced. Imipramine is taken by mouth orally as tablets.

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Tofranil is indicated in- Depressive illness Nocturnal enuresis in children. Tofranil is an original tricyclic antidepressant, a member of the dibenzazepine group of compounds. The mechanism of action of Tofranil is not definitely known. However, it does not act primarily by stimulation of the central nervous system. The clinical effect is hypothesized as being due to the potentiation of adrenergic synapses by blocking uptake of norepinephrine at nerve endings. The mode of action of the drug in controlling childhood enuresis is thought to be apart from its antidepressant effect. Imipramine works by inhibiting the neuronal reuptake of the neurotransmitters norepinephrine and serotonin.

You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years old. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment. Imipramine affects chemicals in the brain that may become unbalanced. If you have any of these conditions, you may not be able to use imipramine, or you may need a dosage adjustment or special tests during treatment. Tell your doctor if you have worsening symptoms of depression or suicidal thoughts during the first several weeks of treatment, or whenever your dose is changed. Your family or other caregivers should also be alert to changes in your mood or symptoms.

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Treating bedwetting isn't an exact science. Since it's very common until 6 years of age, we generally don't try to treat it earlier. At any age, decisions regarding treatment should consider to what extent the problem affects the child and the child's social development. Many young children and their parents are better served by reassurance that there's no physical abnormality than by long-term and expensive therapy of uncertain effectiveness. Treatment may consist of medication, conditioning and behavior modification, or a combination of approaches. There's no medication that cures enuresis — they only treat symptoms.

Avoid; strong anticholinergic and sedative effects; may cause orthostatic hypotension Beers criteria. In short-term studies, antidepressants increased the risk of suicidal thinking and behavior in children, adolescents, and young adults This increase was not seen in patients aged over 24 years; a slight decrease in suicidal thinking was seen in adults aged over 65 years. In children and young adults, risks must be weighed against the benefits of taking antidepressants. Patients should be monitored closely for changes in behavior, clinical worsening, and suicidal tendencies; this should be done during the initial months of therapy and dosage adjustments. Worsening behavior and suicidal tendencies that are not part of the presenting symptoms may require discontinuation of therapy. Lactation: Distributed in breast milk; do not nurse AAP states effect on nursing infants is unknown but may be of concern.

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Keep your celebrex cheap canada appointments with your doctor. This is so your doctor can check on your progress. Imipramine can make you feel sleepy. If this happens, do not drive and do not use tools or machines. It is generally prescribed for the treatment of depression in adults. The exact cause of depression is not known.

It is also effective in treating anxiety and panic disorder. The drug is also used to treat bedwetting. Overdose can result in death. The drug appears to work by increasing levels of serotonin and norepinephrine and by blocking certain serotonin, adrenergic, histamine, and cholinergic receptors. Imipramine and the other TCAs have decreased in use in recent decades due to the introduction of the selective serotonin reuptake inhibitors SSRIs, which have fewer side effects and are safer in overdose.

Imipramine, sold under the brand name Tofranil, among others, is a tricyclic antidepressant TCA mainly used in the treatment of depression. It is also effective in treating anxiety and panic disorder. Imipramine is taken by mouth. Common side effects of imipramine include dry mouth, drowsiness, dizziness, low blood pressure, rapid heart rate, urinary retention, and electrocardiogram changes. Overdose of the medication can result in death. Imipramine appears to work by increasing levels of serotonin and norepinephrine and by blocking certain serotonin, adrenergic, histamine, and cholinergic receptors.

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